Research: Proteomics

Focus Areas


  • Regulation of HIV-1 transcription by host cell CDK2 and protein phosphatase-1
  • Effect of iron chelators and hypoxia on activation of HIV-1 transcription
  • Design of small molecule inhibitors that target phosphatase-1 and inhibit HIV-1
  • Effect of abnormal hypoxic response in Sickle Cell Disease and Chuvash polycythemia in development of pulmonary hypertension
  • Design small molecule PP1 inhibitors to prevent sickling of Sickle Cell Disease red blood cells